Metabolites

Metabolite Analysis for Biopharmaceutical Processes

Metabolites are small intermediary molecules formed in biochemical pathways and are central to cell signalling, regulation of cellular functions and energy production. In biopharmaceutical manufacturing, targeted metabolite analysis provides key insights into cell culture conditions, such as nutrient status, oxygen supply and overall metabolic state, enabling you to improve cell growth, productivity and product quality.

Beyond real-time assessment of cell growth and culture performance, metabolite profiling can also reveal process-related impurities, including microbiological contaminants and unwanted by-products, making it a powerful tool for process monitoring, troubleshooting and quality control.

At Biofidus, we offer standardized chromatographic assays for a broad range of metabolites, including amino acids, organic acids, polyamines, surfactants, sugars, fatty acids, vitamins, nucleotides, secondary messengers and process-related impurities.

In line with your needs, we adapt and, if required, qualify our platform methods to address your specific process, matrix and analytical questions.

Get in contact with our expert to find the optimal strategy for your project and to speak directly from scientist to scientist.

Our Capabilities

  • Quantification and identification of metabolites and impurities
  • Assessment of source and impact on safety of detected metabolites
  • Guidance on process optimization
  • Method qualification
  • Stability studies
  • Forced degradation studies

Just what you need? Contact us!

Analytical techniques

Tell us about Your Project

We‘ll advise you to define your assay needs.

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Our Expert

Please reach out to our expert Dr. Tobias Luttermann for all inquiries regarding small molecules.
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